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Repaglinide

CHEMBL1272 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
452.6 g/mol
LogP
5.2
Phase
4

A short-acting insulin secretagogue used to control blood sugar levels in type 2 diabetes by stimulating the pancreas to release insulin specifically around mealtimes. It is taken before each meal and its rapid action helps reduce post-meal blood sugar spikes.

Molekularmasse

452,6000 g/mol

LogP

5,20

TPSA

78,90 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Ovarian Cancer Cardiovascular Disease Rheumatoid Arthritis Melanoma Chronic Kidney Disease Stroke Obesity Lymphoma Type 2 Diabetes Hypertension Gout Malaria Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCOc1cc(CC(=O)N[C@@H](CC(C)C)c2ccccc2N2CCCCC2)ccc1C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C27H36N2O4

                    

                    
                    

                        
HBD / HBA

                        
2 / 5

                    

                    
                    

                        
Rotierbare Bindungen

                        
10

                    

                    
                    
                    

                        
Schwere Atome

                        
33

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
A short-acting insulin secretagogue used to control blood sugar levels in type 2 diabetes by stimulating the pancreas to release insulin specifically around mealtimes. It is taken before each meal and its rapid action helps reduce post-meal blood sugar spikes.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Repaglinide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1272.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 65981.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.