Secnidazole

CHEMBL498847 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

185.2 g/mol

LogP

0.2

Phase

4

Secnidazole is a 5-nitroimidazole antiprotozoal and antibacterial agent with a longer half-life than metronidazole, approved for single-dose treatment of bacterial vaginosis and trichomoniasis. Its active nitroimidazole moiety is reduced intracellularly to cytotoxic intermediates that disrupt DNA integrity in anaerobic bacteria and parasites. Single-dose oral administration improves adherence compared to multi-day regimens.

Molekularmasse

185,1800 g/mol

LogP

0,20

TPSA

83,90 Å²

Lipinski-Regel der Fünf

Bestanden

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

Cc1ncc([N+](=O)[O-])n1CC(C)O

InChI

InChI=1S/C7H11N3O3/c1-5(11)4-9-6(2)8-3-7(9)10(12)13/h3,5,11H,4H2,1-2H3

Molecular Formula

C7H11N3O3

HBD / HBA

1 / 4

Rotierbare Bindungen

2

Schwere Atome

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Secnidazole is a 5-nitroimidazole antiprotozoal and antibacterial agent with a longer half-life than metronidazole, approved for single-dose treatment of bacterial vaginosis and trichomoniasis. Its active nitroimidazole moiety is reduced intracellularly to cytotoxic intermediates that disrupt DNA integrity in anaerobic bacteria and parasites. Single-dose oral administration improves adherence compared to multi-day regimens.

Yes, Secnidazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL498847. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 71815. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Schnelldaten

Formel: C7H11N3O3
Synonyme: 1

Externe Links

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.