Sitagliptin Hydrochloride Monohydrate

CHEMBL6068334 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
461.8 g/mol
LogP
Phase
4

A hydrochloride salt form of sitagliptin with the same therapeutic properties. This once-daily pill helps control blood sugar in type 2 diabetes by preventing the breakdown of incretin hormones that naturally stimulate insulin release after eating.

Molekularmasse

461,7900 g/mol

TPSA

78,00 Ų

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

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SMILES

Cl.N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F.O

InChI

InChI=1S/C16H15F6N5O.ClH.H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22;;/h4,6,9H,1-3,5,7,23H2;1H;1H2/t9-;;/m1../s1

Molecular Formula

C16H18ClF6N5O2

HBD / HBA

3 / 11

Rotierbare Bindungen

4

Schwere Atome

30

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

A hydrochloride salt form of sitagliptin with the same therapeutic properties. This once-daily pill helps control blood sugar in type 2 diabetes by preventing the breakdown of incretin hormones that naturally stimulate insulin release after eating.

Yes, Sitagliptin Hydrochloride Monohydrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6068334. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 91827430. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.