Sodium Iodide I 123

CHEMBL1201083 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
145.9 g/mol
LogP
Phase
4

Sodium iodide I-123 is a radioactive iodine isotope used for diagnostic thyroid scintigraphy and thyroid uptake measurements, providing high-resolution gamma camera imaging with lower radiation dose compared to iodine-131. The iodide ion is selectively concentrated by thyroid follicular cells via the sodium-iodide symporter, allowing assessment of thyroid morphology, function, and nodule characterization. Iodine-123 emits gamma photons at 159 keV with a 13.2-hour half-life optimal for diagnostic imaging.

Molekularmasse

145,8954 g/mol

TPSA

0,00 Ų

Wirkmechanismus

Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.

2D-Struktur

SVG PNG

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SMILES

[123I-].[Na+]

InChI

InChI=1S/HI.Na/h1H;/q;+1/p-1/i1-4;

Molecular Formula

INa

HBD / HBA

- / 1

Rotierbare Bindungen

0

Schwere Atome

2

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Sodium iodide I-123 is a radioactive iodine isotope used for diagnostic thyroid scintigraphy and thyroid uptake measurements, providing high-resolution gamma camera imaging with lower radiation dose compared to iodine-131. The iodide ion is selectively concentrated by thyroid follicular cells via the sodium-iodide symporter, allowing assessment of thyroid morphology, function, and nodule characterization. Iodine-123 emits gamma photons at 159 keV with a 13.2-hour half-life optimal for diagnostic imaging.

Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.

Yes, Sodium Iodide I 123 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201083. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 11954386. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.