Sulfinpyrazone
Sulfinpyrazone is a uricosuric agent and antiplatelet drug used for the treatment of hyperuricemia and chronic gout by inhibiting tubular reabsorption of uric acid in the kidney, increasing renal uric acid excretion and lowering serum urate levels. It also inhibits platelet cyclooxygenase and thromboxane synthesis, with antiplatelet properties that were investigated for prevention of thromboembolic events. It is used as an alternative to probenecid in patients intolerant of allopurinol.
Molekularmasse
404,5000 g/mol
LogP
2,30
TPSA
76,90 Ų
Lipinski-Regel der Fünf
Bestanden
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D-Struktur
Cite this structure
Embed this structure
SMILES
O=C1C(CC[S+]([O-])c2ccccc2)C(=O)N(c2ccccc2)N1c1ccccc1
InChI
InChI=1S/C23H20N2O3S/c26-22-21(16-17-29(28)20-14-8-3-9-15-20)23(27)25(19-12-6-2-7-13-19)24(22)18-10-4-1-5-11-18/h1-15,21H,16-17H2
Molecular Formula
C23H20N2O3S
HBD / HBA
- / 4
Rotierbare Bindungen
6
Schwere Atome
29
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
Sulfinpyrazone is a uricosuric agent and antiplatelet drug used for the treatment of hyperuricemia and chronic gout by inhibiting tubular reabsorption of uric acid in the kidney, increasing renal uric acid excretion and lowering serum urate levels. It also inhibits platelet cyclooxygenase and thromboxane synthesis, with antiplatelet properties that were investigated for prevention of thromboembolic events. It is used as an alternative to probenecid in patients intolerant of allopurinol.
Yes, Sulfinpyrazone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL832. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5342. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="sulfinpyrazone"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/sulfinpyrazone/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/sulfinpyrazone/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/sulfinpyrazone/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="sulfinpyrazone"></drugfyi-drug>