Tadalafil

CHEMBL779 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

389.4 g/mol

LogP

2.3

Phase

4

This medication relaxes the muscles and blood vessels in the penis to help men achieve and maintain an erection, and is also used to treat the symptoms of an enlarged prostate. In addition, it is prescribed to lower blood pressure in the lungs (pulmonary arterial hypertension), allowing patients to exercise more easily. It should not be taken with nitrate medications due to the risk of a dangerous drop in blood pressure.

Molekularmasse

389,4000 g/mol

LogP

2,30

TPSA

74,90 Å²

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Benign Prostatic Hyperplasia Glaucoma Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Parkinson's Disease Stroke Obesity Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Chronic Pain Heart Failure Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure

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SMILES

CN1CC(=O)N2[C@H](c3ccc4c(c3)OCO4)c3[nH]c4ccccc4c3C[C@@H]2C1=O

InChI

InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1

Molecular Formula

C22H19N3O4

HBD / HBA

1 / 4

Rotierbare Bindungen

1

Schwere Atome

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

This medication relaxes the muscles and blood vessels in the penis to help men achieve and maintain an erection, and is also used to treat the symptoms of an enlarged prostate. In addition, it is prescribed to lower blood pressure in the lungs (pulmonary arterial hypertension), allowing patients to exercise more easily. It should not be taken with nitrate medications due to the risk of a dangerous drop in blood pressure.

Yes, Tadalafil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL779. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 110635. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Schnelldaten

Formel: C22H19N3O4
Synonyme: 9

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.