Technetium Tc 99M Bicisate

CHEMBL1237111 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

434.3 g/mol

LogP

—

Phase

4

Technetium Tc 99m bicisate (99mTc-ECD) is a lipophilic ester that diffuses freely across the blood-brain barrier and is subsequently hydrolyzed intracellularly to a charged form that is retained in brain tissue, enabling SPECT cerebral perfusion imaging. It is used in the evaluation of stroke, epilepsy, dementia, and other cerebrovascular conditions. See technetium-bicisate for additional pharmacological details.

Molekularmasse

434,3000 g/mol

TPSA

68,60 Å²

Therapeutische Bereiche

Epilepsy

Pharmacokinetics (PK)

Pharmacodynamics (PD)

SMILES

CCOC(=O)[C@H](C[S-])NCC[N-][C@@H](C[S-])C(=O)OCC.[O-2].[Tc]

InChI

InChI=1S/C12H23N2O4S2.O.Tc/c1-3-17-11(15)9(7-19)13-5-6-14-10(8-20)12(16)18-4-2;;/h9-10,13,19-20H,3-8H2,1-2H3;;/q-1;-2;/p-2/t9-,10-;;/m0../s1

Molecular Formula

C12H21N2O5S2Tc-5

HBD / HBA

1 / 9

Rotierbare Bindungen

13

Schwere Atome

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Technetium Tc 99m bicisate (99mTc-ECD) is a lipophilic ester that diffuses freely across the blood-brain barrier and is subsequently hydrolyzed intracellularly to a charged form that is retained in brain tissue, enabling SPECT cerebral perfusion imaging. It is used in the evaluation of stroke, epilepsy, dementia, and other cerebrovascular conditions. See technetium-bicisate for additional pharmacological details.

Yes, Technetium Tc 99M Bicisate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1237111. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 155491161. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Schnelldaten

Formel: C12H21N2O5S2Tc-5

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.