Tenofovir Disoproxil Phosphate
Tenofovir disoproxil phosphate is a phosphate salt formulation of tenofovir disoproxil, an NRTI prodrug used for HIV/AIDS treatment and prevention. See tenofovir-disoproxil for complete pharmacological details. This formulation has been investigated as an alternative to the fumarate salt.
Molekularmasse
617,4000 g/mol
TPSA
263,00 Ų
Therapeutische Bereiche
Wirkmechanismus
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
2D-Struktur
Cite this structure
Embed this structure
SMILES
CC(C)OC(=O)OCOP(=O)(CO[C@H](C)Cn1cnc2c(N)ncnc21)OCOC(=O)OC(C)C.O=P(O)(O)O
InChI
InChI=1S/C19H30N5O10P.H3O4P/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;1-5(2,3)4/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);(H3,1,2,3,4)/t14-;/m1./s1
Molecular Formula
C19H33N5O14P2
HBD / HBA
4 / 18
Rotierbare Bindungen
17
Schwere Atome
40
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
Tenofovir disoproxil phosphate is a phosphate salt formulation of tenofovir disoproxil, an NRTI prodrug used for HIV/AIDS treatment and prevention. See tenofovir-disoproxil for complete pharmacological details. This formulation has been investigated as an alternative to the fumarate salt.
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Yes, Tenofovir Disoproxil Phosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6068341. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 71714119. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="tenofovir-disoproxil-phosphate"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/tenofovir-disoproxil-phosphate/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/tenofovir-disoproxil-phosphate/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/tenofovir-disoproxil-phosphate/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="tenofovir-disoproxil-phosphate"></drugfyi-drug>