Tiotropium

CHEMBL1900528 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

392.5 g/mol

LogP

2.3

Phase

4

This long-acting bronchodilator is used once daily as a maintenance treatment for chronic obstructive pulmonary disease (COPD) and sometimes asthma, to keep the airways open and reduce breathlessness. It works by blocking muscarinic receptors in the airway smooth muscle, causing the airways to relax and widen. It is delivered via a special inhaler device and is not a rescue medication for sudden breathlessness.

Molekularmasse

392,5000 g/mol

LogP

2,30

TPSA

116,00 Å²

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Glaucoma Cardiovascular Disease Non-Small Cell Lung Cancer Asthma Chronic Obstructive Pulmonary Disease Obesity Tuberculosis Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

C[N+]1(C)[C@@H]2C[C@@H](OC(=O)C(O)(c3cccs3)c3cccs3)C[C@H]1[C@@H]1O[C@@H]12

InChI

InChI=1S/C19H22NO4S2/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15/h3-8,11-13,16-17,22H,9-10H2,1-2H3/q+1/t11-,12-,13+,16-,17+

Molecular Formula

C19H22NO4S2+

HBD / HBA

1 / 6

Rotierbare Bindungen

5

Schwere Atome

26

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

This long-acting bronchodilator is used once daily as a maintenance treatment for chronic obstructive pulmonary disease (COPD) and sometimes asthma, to keep the airways open and reduce breathlessness. It works by blocking muscarinic receptors in the airway smooth muscle, causing the airways to relax and widen. It is delivered via a special inhaler device and is not a rescue medication for sudden breathlessness.

Yes, Tiotropium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1900528. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5487427. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Schnelldaten

Formel: C19H22NO4S2+
Synonyme: 4

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.