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Torsemide

CHEMBL1148 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
348.4 g/mol
LogP
2.7
Phase
4

This loop diuretic medication helps the kidneys remove excess fluid and salt from the body, and is used to treat fluid retention (edema) caused by heart failure, kidney disease, or liver cirrhosis, as well as high blood pressure. It acts on the kidney's loop of Henle to block sodium reabsorption, producing a strong diuretic effect. Potassium levels should be monitored as the medication can cause potassium loss.

Molekularmasse

348,4000 g/mol

LogP

2,70

TPSA

109,00 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Cardiovascular Disease Chronic Kidney Disease Hypertension Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Cc1cccc(Nc2ccncc2S(=O)(=O)NC(=O)NC(C)C)c1

                

                

                
                

                    
InChI

                    
InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H20N4O3S

                    

                    
                    

                        
HBD / HBA

                        
3 / 5

                    

                    
                    

                        
Rotierbare Bindungen

                        
5

                    

                    
                    
                    

                        
Schwere Atome

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
This loop diuretic medication helps the kidneys remove excess fluid and salt from the body, and is used to treat fluid retention (edema) caused by heart failure, kidney disease, or liver cirrhosis, as well as high blood pressure. It acts on the kidney's loop of Henle to block sodium reabsorption, producing a strong diuretic effect. Potassium levels should be monitored as the medication can cause potassium loss.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Torsemide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1148.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 41781.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.