Trimethaphan Camsylate

CHEMBL1245 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

596.8 g/mol

LogP

—

Phase

4

Trimethaphan camsylate is the camphorsulfonate salt of trimethaphan, a ganglionic blocking agent that blocks nicotinic receptors at autonomic ganglia to produce controlled hypotension. It was administered intravenously for acute hypertensive crises and to create deliberate hypotension during surgical procedures. The camsylate salt form was used in the marketed parenteral formulation.

Molekularmasse

596,8000 g/mol

TPSA

107,00 Å²

Therapeutische Bereiche

Obesity Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

CC1(C)C2CCC1(CS(=O)(=O)[O-])C(=O)C2.O=C1N(Cc2ccccc2)C2C[S+]3CCCC3C2N1Cc1ccccc1

InChI

InChI=1S/C22H25N2OS.C10H16O4S/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h1-6,8-11,19-21H,7,12-16H2;7H,3-6H2,1-2H3,(H,12,13,14)/q+1;/p-1

Molecular Formula

C32H40N2O5S2

HBD / HBA

- / 5

Rotierbare Bindungen

5

Schwere Atome

41

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Trimethaphan camsylate is the camphorsulfonate salt of trimethaphan, a ganglionic blocking agent that blocks nicotinic receptors at autonomic ganglia to produce controlled hypotension. It was administered intravenously for acute hypertensive crises and to create deliberate hypotension during surgical procedures. The camsylate salt form was used in the marketed parenteral formulation.

Yes, Trimethaphan Camsylate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1245. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 44602409. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

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Formel: C32H40N2O5S2

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.