Tyropanoic Acid

CHEMBL1201261 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
641.0 g/mol
LogP
4.6
Phase
4

Tyropanoic acid is an iodinated radiocontrast medium used for oral cholecystography to visualize the gallbladder and biliary tract by concentrating iodine in bile after hepatic uptake. It acts as a thyroid hormone synthesis inhibitor by blocking the conversion of T4 to T3, and was investigated for short-term management of thyrotoxicosis. Its radiographic and antithyroid properties made it useful in both diagnostic imaging and emergency thyroid management.

Molekularmasse

641,0200 g/mol

LogP

4,60

TPSA

66,40 Ų

Lipinski-Regel der Fünf

Bestanden

Wirkmechanismus

Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.

2D-Struktur

SVG PNG

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SMILES

CCCC(=O)Nc1c(I)cc(I)c(CC(CC)C(=O)O)c1I

InChI

InChI=1S/C15H18I3NO3/c1-3-5-12(20)19-14-11(17)7-10(16)9(13(14)18)6-8(4-2)15(21)22/h7-8H,3-6H2,1-2H3,(H,19,20)(H,21,22)

Molecular Formula

C15H18I3NO3

HBD / HBA

2 / 3

Rotierbare Bindungen

7

Schwere Atome

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Tyropanoic acid is an iodinated radiocontrast medium used for oral cholecystography to visualize the gallbladder and biliary tract by concentrating iodine in bile after hepatic uptake. It acts as a thyroid hormone synthesis inhibitor by blocking the conversion of T4 to T3, and was investigated for short-term management of thyrotoxicosis. Its radiographic and antithyroid properties made it useful in both diagnostic imaging and emergency thyroid management.

Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.

Yes, Tyropanoic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201261. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5611. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.