Ytterbium Pentetate
Ytterbium pentetate (169Yb-DTPA) is a radioactive chelate complex where the rare earth element ytterbium-169 is conjugated to diethylenetriaminepentaacetic acid (DTPA), used as a radiopharmaceutical for cisternography and evaluation of cerebrospinal fluid dynamics by intrathecal injection. The radiolabeled complex distributes through the CSF spaces and can be imaged with gamma camera or SPECT to detect CSF leaks, communicating hydrocephalus, and CSF flow obstruction. Its gamma emission profile makes it suitable for nuclear medicine CSF imaging.
Molekularmasse
566,4000 g/mol
TPSA
196,00 Ų
Wirkmechanismus
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
2D-Struktur
Cite this structure
Embed this structure
SMILES
O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)CC(=O)O.[Yb]
InChI
InChI=1S/C14H23N3O10.Yb/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);
Molecular Formula
C14H23N3O10Yb
HBD / HBA
5 / 13
Rotierbare Bindungen
16
Schwere Atome
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
Ytterbium pentetate (169Yb-DTPA) is a radioactive chelate complex where the rare earth element ytterbium-169 is conjugated to diethylenetriaminepentaacetic acid (DTPA), used as a radiopharmaceutical for cisternography and evaluation of cerebrospinal fluid dynamics by intrathecal injection. The radiolabeled complex distributes through the CSF spaces and can be imaged with gamma camera or SPECT to detect CSF leaks, communicating hydrocephalus, and CSF flow obstruction. Its gamma emission profile makes it suitable for nuclear medicine CSF imaging.
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
Yes, Ytterbium Pentetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2219546. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 177638023. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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