Aspirin vs Hydrochlorothiazide

## Aspirin vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Aspirin** and **Hydrochlorothiazide**.

## Mechanism of Action

**Aspirin**: Irreversibly inhibits cyclooxygenase-1 and -2.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Aspirin — 2-3 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Aspirin — C9H8O4; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Aspirin — 180.1580 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Aspirin — Small molecule; Hydrochlorothiazide — Small molecule.