Canagliflozin vs Trimethoprim

## Canagliflozin vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Canagliflozin** and **Trimethoprim**.

## Mechanism of Action

**Canagliflozin**: Selective SGLT2 inhibitor reducing renal glucose reabsorption and lowering blood glucose.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Canagliflozin — 10.6 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Canagliflozin — C24H25FO5S; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Canagliflozin — 444.5170 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Canagliflozin — Small molecule; Trimethoprim — Small molecule.