Captopril vs Doxycycline

## Captopril vs Doxycycline: Overview

This comparison examines the pharmacological differences between **Captopril** and **Doxycycline**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Doxycycline**: Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Doxycycline — 18-22 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Doxycycline — C22H24N2O8.

**Molecular Weight**: Captopril — 217.2850 g/mol; Doxycycline — 444.4350 g/mol.

**Type**: Captopril — Small molecule; Doxycycline — Small molecule.