Celecoxib vs Ibuprofen

## Celecoxib vs Ibuprofen: Overview

This comparison examines the pharmacological differences between **Celecoxib** and **Ibuprofen**.

## Mechanism of Action

**Celecoxib**: Selective COX-2 inhibitor.

**Ibuprofen**: Non-selective COX inhibitor reducing prostaglandin synthesis.

## Pharmacokinetics

**Half-life**: Celecoxib — 11 hours; Ibuprofen — 2-4 hours.

## Chemical Properties

**Molecular Formula**: Celecoxib — C17H14F3N3O2S; Ibuprofen — C13H18O2.

**Molecular Weight**: Celecoxib — 381.3730 g/mol; Ibuprofen — 206.2810 g/mol.

**Type**: Celecoxib — Small molecule; Ibuprofen — Small molecule.