Citalopram vs Topiramate

## Citalopram vs Topiramate: Overview

This comparison examines the pharmacological differences between **Citalopram** and **Topiramate**.

## Mechanism of Action

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

**Topiramate**: Multiple mechanisms: Na+ channel block, GABA enhancement, glutamate inhibition.

## Pharmacokinetics

**Half-life**: Citalopram — 35 hours; Topiramate — 21 hours.

## Chemical Properties

**Molecular Formula**: Citalopram — C20H21FN2O; Topiramate — C12H21NO8S.

**Molecular Weight**: Citalopram — 324.3920 g/mol; Topiramate — 339.3630 g/mol.

**Type**: Citalopram — Small molecule; Topiramate — Small molecule.