Cyclosporine vs Hydrochlorothiazide

## Cyclosporine vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Cyclosporine** and **Hydrochlorothiazide**.

## Mechanism of Action

**Cyclosporine**: Calcineurin inhibitor suppressing T-cell activation.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Cyclosporine — 6-12 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Cyclosporine — C62H111N11O12; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Cyclosporine — 1202.6100 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Cyclosporine — Protein; Hydrochlorothiazide — Small molecule.