Diazepam vs Tofacitinib

## Diazepam vs Tofacitinib: Overview

This comparison examines the pharmacological differences between **Diazepam** and **Tofacitinib**.

## Mechanism of Action

**Diazepam**: Positive allosteric modulator of GABA-A receptors.

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

## Pharmacokinetics

**Half-life**: Diazepam — 20-100 hours; Tofacitinib — 3.2 hours.

## Chemical Properties

**Molecular Formula**: Diazepam — C16H13ClN2O; Tofacitinib — C16H20N6O.

**Molecular Weight**: Diazepam — 284.7400 g/mol; Tofacitinib — 312.3700 g/mol.

**Type**: Diazepam — Small molecule; Tofacitinib — Small molecule.