Dulaglutide vs Semaglutide

## Dulaglutide vs Semaglutide: Overview

This comparison examines the pharmacological differences between **Dulaglutide** and **Semaglutide**.

## Mechanism of Action

**Dulaglutide**: GLP-1 receptor agonist fused to Fc fragment; enhances glucose-dependent insulin secretion.

**Semaglutide**: GLP-1 receptor agonist with enhanced albumin binding for extended action.

## Pharmacokinetics

**Half-life**: Dulaglutide — 5 days; Semaglutide — 7 days.

## Chemical Properties

**Type**: Dulaglutide — Protein; Semaglutide — Protein.