Duloxetine vs Loratadine

## Duloxetine vs Loratadine: Overview

This comparison examines the pharmacological differences between **Duloxetine** and **Loratadine**.

## Mechanism of Action

**Duloxetine**: Serotonin-norepinephrine reuptake inhibitor (SNRI).

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

## Pharmacokinetics

**Half-life**: Duloxetine — 12 hours; Loratadine — 8 hours.

## Chemical Properties

**Molecular Formula**: Duloxetine — C18H19NOS; Loratadine — C22H23ClN2O2.

**Molecular Weight**: Duloxetine — 297.4150 g/mol; Loratadine — 382.8800 g/mol.

**Type**: Duloxetine — Small molecule; Loratadine — Small molecule.