Enalapril vs Tofacitinib

## Enalapril vs Tofacitinib: Overview

This comparison examines the pharmacological differences between **Enalapril** and **Tofacitinib**.

## Mechanism of Action

**Enalapril**: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

## Pharmacokinetics

**Half-life**: Enalapril — 11 hours; Tofacitinib — 3.2 hours.

## Chemical Properties

**Molecular Formula**: Enalapril — C20H28N2O5; Tofacitinib — C16H20N6O.

**Molecular Weight**: Enalapril — 376.4470 g/mol; Tofacitinib — 312.3700 g/mol.

**Type**: Enalapril — Small molecule; Tofacitinib — Small molecule.