Exenatide vs Semaglutide

## Exenatide vs Semaglutide: Overview

This comparison examines the pharmacological differences between **Exenatide** and **Semaglutide**.

## Mechanism of Action

**Exenatide**: Synthetic exendin-4 GLP-1 receptor agonist enhancing glucose-dependent insulin secretion.

**Semaglutide**: GLP-1 receptor agonist with enhanced albumin binding for extended action.

## Pharmacokinetics

**Half-life**: Exenatide — 2.4 hours; Semaglutide — 7 days.

## Chemical Properties

**Type**: Exenatide — Protein; Semaglutide — Protein.