Hydrochlorothiazide vs Pravastatin

## Hydrochlorothiazide vs Pravastatin: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Pravastatin**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Pravastatin**: Competitive inhibitor of HMG-CoA reductase.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Pravastatin — 1.8 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Pravastatin — C23H36O7.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Pravastatin — 424.5280 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Pravastatin — Small molecule.