Ibuprofen vs Sitagliptin

## Ibuprofen vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Ibuprofen** and **Sitagliptin**.

## Mechanism of Action

**Ibuprofen**: Non-selective COX inhibitor reducing prostaglandin synthesis.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Ibuprofen — 2-4 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Ibuprofen — C13H18O2; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Ibuprofen — 206.2810 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Ibuprofen — Small molecule; Sitagliptin — Small molecule.