Lamotrigine vs Phenytoin

## Lamotrigine vs Phenytoin: Overview

This comparison examines the pharmacological differences between **Lamotrigine** and **Phenytoin**.

## Mechanism of Action

**Lamotrigine**: Sodium channel blocker inhibiting glutamate release.

**Phenytoin**: Sodium channel blocker stabilizing inactive state.

## Pharmacokinetics

**Half-life**: Lamotrigine — 25 hours; Phenytoin — 22 hours.

## Chemical Properties

**Molecular Formula**: Lamotrigine — C9H7Cl2N5; Phenytoin — C15H12N2O2.

**Molecular Weight**: Lamotrigine — 256.0910 g/mol; Phenytoin — 252.2680 g/mol.

**Type**: Lamotrigine — Small molecule; Phenytoin — Small molecule.