Methylprednisolone vs Prednisone

## Methylprednisolone vs Prednisone: Overview

This comparison examines the pharmacological differences between **Methylprednisolone** and **Prednisone**.

## Mechanism of Action

**Methylprednisolone**: Intermediate-acting synthetic glucocorticoid.

**Prednisone**: Synthetic corticosteroid; suppresses inflammation via glucocorticoid receptor.

## Pharmacokinetics

**Half-life**: Methylprednisolone — 18-36 hours; Prednisone — 2-3 hours.

## Chemical Properties

**Molecular Formula**: Methylprednisolone — C22H30O5; Prednisone — C21H26O5.

**Molecular Weight**: Methylprednisolone — 374.4710 g/mol; Prednisone — 358.4280 g/mol.

**Type**: Methylprednisolone — Small molecule; Prednisone — Small molecule.