Phenytoin vs Sildenafil

## Phenytoin vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Phenytoin** and **Sildenafil**.

## Mechanism of Action

**Phenytoin**: Sodium channel blocker stabilizing inactive state.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Phenytoin — 22 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Phenytoin — C15H12N2O2; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Phenytoin — 252.2680 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Phenytoin — Small molecule; Sildenafil — Small molecule.