Semaglutide vs Sitagliptin

## Semaglutide vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Semaglutide** and **Sitagliptin**.

## Mechanism of Action

**Semaglutide**: GLP-1 receptor agonist with enhanced albumin binding for extended action.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Semaglutide — 7 days; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Semaglutide — N/A; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Semaglutide — N/A; Sitagliptin — 407.3140 g/mol.

**Type**: Semaglutide — Protein; Sitagliptin — Small molecule.