Sildenafil vs Venlafaxine

## Sildenafil vs Venlafaxine: Overview

This comparison examines the pharmacological differences between **Sildenafil** and **Venlafaxine**.

## Mechanism of Action

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

**Venlafaxine**: Serotonin-norepinephrine reuptake inhibitor (SNRI).

## Pharmacokinetics

**Half-life**: Sildenafil — 4 hours; Venlafaxine — 5 hours.

## Chemical Properties

**Molecular Formula**: Sildenafil — C22H30N6O4S; Venlafaxine — C17H27NO2.

**Molecular Weight**: Sildenafil — 474.5800 g/mol; Venlafaxine — 277.4020 g/mol.

**Type**: Sildenafil — Small molecule; Venlafaxine — Small molecule.