Amantadine
An antiviral and dopaminergic medication with dual uses: it was originally developed to prevent influenza A infection, and it also treats the symptoms of Parkinson's disease and drug-induced movement disorders by increasing dopamine activity and blocking NMDA glutamate receptors in the brain. It can reduce involuntary movements (dyskinesias) in Parkinson's patients.
Peso molecular
151,2500 g/mol
LogP
2,40
TPSA
26,00 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
NC12CC3CC(CC(C3)C1)C2
InChI
InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
Molecular Formula
C10H17N
HBD / HBA
1 / 1
Enlaces Rotables
0
Átomos Pesados
11
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
An antiviral and dopaminergic medication with dual uses: it was originally developed to prevent influenza A infection, and it also treats the symptoms of Parkinson's disease and drug-induced movement disorders by increasing dopamine activity and blocking NMDA glutamate receptors in the brain. It can reduce involuntary movements (dyskinesias) in Parkinson's patients.
Yes, Amantadine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL660. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2130. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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