Amoxicillin
A broad-spectrum penicillin-type antibiotic that works by interfering with bacteria's ability to build their cell walls, causing them to burst and die. It is one of the most widely prescribed antibiotics for respiratory, ear, and urinary tract infections.
Peso molecular
365,4050 g/mol
LogP
-2,00
TPSA
158,00 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Clases de fármacos
Mecanismo de acción
Inhibits bacterial cell wall synthesis by binding to PBPs.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits bacterial cell wall synthesis by binding to PBPs.
Estructura 2D
Cite this structure
Embed this structure
SMILES
CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O
InChI
InChI=1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1
Molecular Formula
C16H19N3O5S
HBD / HBA
4 / 7
Enlaces Rotables
4
Átomos Pesados
25
Amoxicillin may slightly potentiate warfarin by reducing gut flora that synthesize vitamin K2, though the effect is generally small and inconsistent.
Amoxicillin can reduce the renal clearance of methotrexate by inhibiting tubular secretion, increasing methotrexate plasma levels and risk of toxicity.
The combination of allopurinol and amoxicillin is associated with a markedly increased incidence of skin rashes (primarily maculopapular), though the rash is usually non-severe and reversible.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A broad-spectrum penicillin-type antibiotic that works by interfering with bacteria's ability to build their cell walls, causing them to burst and die. It is one of the most widely prescribed antibiotics for respiratory, ear, and urinary tract infections.
Inhibits bacterial cell wall synthesis by binding to PBPs.
Key pharmacokinetic parameters for Amoxicillin: Half-life: 1-1.5 hours.
Yes, Amoxicillin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
Same Drug Class
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1082. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 33613. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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