Apraclonidine
An alpha-2 adrenergic agonist used as eye drops to lower intraocular pressure in glaucoma by reducing the production of aqueous humor inside the eye. It is particularly useful for controlling pressure spikes following laser eye procedures.
Peso molecular
245,1100 g/mol
LogP
1,30
TPSA
62,40 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
Nc1cc(Cl)c(N=C2NCCN2)c(Cl)c1
InChI
InChI=1S/C9H10Cl2N4/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2,12H2,(H2,13,14,15)
Molecular Formula
C9H10Cl2N4
HBD / HBA
3 / 2
Enlaces Rotables
2
Átomos Pesados
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
An alpha-2 adrenergic agonist used as eye drops to lower intraocular pressure in glaucoma by reducing the production of aqueous humor inside the eye. It is particularly useful for controlling pressure spikes following laser eye procedures.
Yes, Apraclonidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL647. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2216. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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