Atovaquone
An antiparasitic and antifungal agent that disrupts the mitochondrial electron transport chain in protozoa and certain fungi, preventing them from producing energy. It is used to treat and prevent Pneumocystis pneumonia and toxoplasmosis.
Peso molecular
366,8000 g/mol
LogP
5,20
TPSA
54,40 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Mecanismo de acción
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Estructura 2D
Cite this structure
Embed this structure
SMILES
O=C1C(O)=C([C@H]2CC[C@H](c3ccc(Cl)cc3)CC2)C(=O)c2ccccc21
InChI
InChI=1S/C22H19ClO3/c23-16-11-9-14(10-12-16)13-5-7-15(8-6-13)19-20(24)17-3-1-2-4-18(17)21(25)22(19)26/h1-4,9-13,15,26H,5-8H2/t13-,15-
Molecular Formula
C22H19ClO3
HBD / HBA
1 / 3
Enlaces Rotables
2
Átomos Pesados
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
An antiparasitic and antifungal agent that disrupts the mitochondrial electron transport chain in protozoa and certain fungi, preventing them from producing energy. It is used to treat and prevent Pneumocystis pneumonia and toxoplasmosis.
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Yes, Atovaquone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1450. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 74989. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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