Axitinib

CHEMBL1289926 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

386.5 g/mol

LogP

4.2

Phase

4

A potent inhibitor of vascular endothelial growth factor receptors that cuts off the blood supply that tumors need to grow, used for renal cell carcinoma. It is taken by mouth and can cause high blood pressure as a common side effect.

Peso molecular

386,5000 g/mol

LogP

4,20

TPSA

96,00 Å²

Regla de cinco de Lipinski

Cumple

Áreas terapéuticas

Cáncer colorrectal Cáncer de mama Cáncer de ovario Cáncer de páncreas Cáncer de próstata Cáncer de pulmón de células no pequeñas Cáncer de tiroides Cáncer de vejiga Degeneración macular relacionada con la edad Endometriosis Leucemia Linfoma Melanoma

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

SVG PNG

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SMILES

CNC(=O)c1ccccc1Sc1ccc2c(/C=C/c3ccccn3)n[nH]c2c1

InChI

InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+

Molecular Formula

C22H18N4OS

HBD / HBA

2 / 4

Enlaces Rotables

5

Átomos Pesados

28

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

A potent inhibitor of vascular endothelial growth factor receptors that cuts off the blood supply that tumors need to grow, used for renal cell carcinoma. It is taken by mouth and can cause high blood pressure as a common side effect.

Yes, Axitinib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1289926. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6450551. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Estructura

Datos Rápidos

Fórmula: C22H18N4OS
Sinónimos: 1

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.