Bacampicillin
A prodrug of ampicillin that is rapidly absorbed from the gastrointestinal tract and hydrolyzed to the active antibiotic, providing higher blood levels than oral ampicillin alone.
Peso molecular
465,5000 g/mol
LogP
2,70
TPSA
163,00 Ų
Regla de cinco de Lipinski
Cumple
Mecanismo de acción
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Estructura 2D
Cite this structure
Embed this structure
SMILES
CCOC(=O)OC(C)OC(=O)[C@@H]1N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccccc3)[C@H]2SC1(C)C
InChI
InChI=1S/C21H27N3O7S/c1-5-29-20(28)31-11(2)30-19(27)15-21(3,4)32-18-14(17(26)24(15)18)23-16(25)13(22)12-9-7-6-8-10-12/h6-11,13-15,18H,5,22H2,1-4H3,(H,23,25)/t11?,13-,14-,15+,18-/m1/s1
Molecular Formula
C21H27N3O7S
HBD / HBA
2 / 9
Enlaces Rotables
10
Átomos Pesados
32
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A prodrug of ampicillin that is rapidly absorbed from the gastrointestinal tract and hydrolyzed to the active antibiotic, providing higher blood levels than oral ampicillin alone.
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Yes, Bacampicillin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1583. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 441397. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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