Beclomethasone Dipropionate
An inhaled and intranasal corticosteroid that suppresses airway inflammation by blocking the production of multiple inflammatory mediators in epithelial and immune cells. It is a cornerstone treatment for asthma and allergic rhinitis.
Peso molecular
521,0000 g/mol
LogP
3,00
TPSA
107,00 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Mecanismo de acción
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Estructura 2D
Cite this structure
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SMILES
CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@@]21C
InChI
InChI=1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
Molecular Formula
C28H37ClO7
HBD / HBA
1 / 7
Enlaces Rotables
8
Átomos Pesados
36
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
An inhaled and intranasal corticosteroid that suppresses airway inflammation by blocking the production of multiple inflammatory mediators in epithelial and immune cells. It is a cornerstone treatment for asthma and allergic rhinitis.
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Yes, Beclomethasone Dipropionate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200500. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 21700. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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