Carphenazine Maleate

CHEMBL2358147 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

657.7 g/mol

LogP

—

Phase

4

This is the maleate salt form of carphenazine, an older typical antipsychotic of the phenothiazine class. It was used to manage symptoms of psychosis but has been largely superseded by newer antipsychotic medications. Like other phenothiazines, it carries risks of extrapyramidal side effects and tardive dyskinesia.

Peso molecular

657,7000 g/mol

TPSA

222,00 Å²

Mecanismo de acción

Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal side effects.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal …

Estructura 2D

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SMILES

CCC(=O)c1ccc2c(c1)N(CCCN1CCN(CCO)CC1)c1ccccc1S2.O=C(O)/C=C\C(=O)O.O=C(O)/C=C\C(=O)O

InChI

InChI=1S/C24H31N3O2S.2C4H4O4/c1-2-22(29)19-8-9-24-21(18-19)27(20-6-3-4-7-23(20)30-24)11-5-10-25-12-14-26(15-13-25)16-17-28;2*5-3(6)1-2-4(7)8/h3-4,6-9,18,28H,2,5,10-17H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

Molecular Formula

C32H39N3O10S

HBD / HBA

5 / 14

Enlaces Rotables

12

Átomos Pesados

46

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

This is the maleate salt form of carphenazine, an older typical antipsychotic of the phenothiazine class. It was used to manage symptoms of psychosis but has been largely superseded by newer antipsychotic medications. Like other phenothiazines, it carries risks of extrapyramidal side effects and tardive dyskinesia.

Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal side effects.

Yes, Carphenazine Maleate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2358147. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6433356. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Estructura

Datos Rápidos

Fórmula: C32H39N3O10S

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.