Chlorhexidine
A broad-spectrum antiseptic agent that disrupts microbial cell membranes, effective against bacteria, fungi, and some viruses, used extensively for skin and wound disinfection, hand sanitization, and oral hygiene. It binds to skin and mucous membranes for prolonged residual antimicrobial activity. It is a cornerstone of infection control protocols in healthcare settings.
Peso molecular
505,4000 g/mol
LogP
0,10
TPSA
178,00 Ų
Regla de cinco de Lipinski
No cumple
Áreas terapéuticas
Mecanismo de acción
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
Estructura 2D
Cite this structure
Embed this structure
SMILES
N=C(NCCCCCCNC(=N)NC(=N)Nc1ccc(Cl)cc1)NC(=N)Nc1ccc(Cl)cc1
InChI
InChI=1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)
Molecular Formula
C22H30Cl2N10
HBD / HBA
6 / 2
Enlaces Rotables
13
Átomos Pesados
34
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A broad-spectrum antiseptic agent that disrupts microbial cell membranes, effective against bacteria, fungi, and some viruses, used extensively for skin and wound disinfection, hand sanitization, and oral hygiene. It binds to skin and mucous membranes for prolonged residual antimicrobial activity. It is a cornerstone of infection control protocols in healthcare settings.
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
Yes, Chlorhexidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL790. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9552079. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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