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Clonazepam

CHEMBL452 Phase 4 Aprobado Small molecule
Half-Life
30-40 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
315.7 g/mol
LogP
2.4
Phase
4

A long-acting benzodiazepine that enhances GABA activity in the brain, used to prevent and control various types of seizures including absence and myoclonic seizures. It is also prescribed for panic disorder and certain movement disorders.

Peso molecular

315,7150 g/mol

LogP

2,40

TPSA

87,30 Ų

Regla de cinco de Lipinski

Cumple

Áreas terapéuticas

Dolor crónico Epilepsia Esquizofrenia Linfoma Manejo del dolor Trastorno bipolar Trastorno de ansiedad generalizada

Clases de fármacos

N — N - Sistema nervioso

Mecanismo de acción

Long-acting benzodiazepine positive allosteric modulator of GABA-A receptors.

Pharmacokinetics (PK)

Half-Life 30-40 hours

Pharmacodynamics (PD)

Mecanismo

Long-acting benzodiazepine positive allosteric modulator of GABA-A receptors.

Estructura 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
O=C1CN=C(c2ccccc2Cl)c2cc([N+](=O)[O-])ccc2N1

                

                

                
                

                    
InChI

                    
InChI=1S/C15H10ClN3O3/c16-12-4-2-1-3-10(12)15-11-7-9(19(21)22)5-6-13(11)18-14(20)8-17-15/h1-7H,8H2,(H,18,20)

                

                

                

                    
                    

                        
Molecular Formula

                        
C15H10ClN3O3

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
Enlaces Rotables

                        
1

                    

                    
                    
                    

                        
Átomos Pesados

                        
22

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Preguntas frecuentes

                

                    
                    

                        
                        

                            
A long-acting benzodiazepine that enhances GABA activity in the brain, used to prevent and control various types of seizures including absence and myoclonic seizures. It is also prescribed for panic disorder and certain movement disorders.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Long-acting benzodiazepine positive allosteric modulator of GABA-A receptors.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Clonazepam: Half-life: 30-40 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Clonazepam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Acetaminophen
                            Small molecule
                        
                        
                        
                            Aspirin
                            Small molecule
                        
                        
                        
                            Sertraline
                            Small molecule
                        
                        
                        
                            Escitalopram
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL452.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2802.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Aviso médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.