Deserpidine
A rauwolfia alkaloid that depletes catecholamine and serotonin stores in nerve terminals, used historically to treat high blood pressure and certain psychiatric conditions. Like reserpine, it can cause severe depression as a side effect. Its use has been largely abandoned in favor of safer and more effective antihypertensives.
Peso molecular
578,7000 g/mol
LogP
4,10
TPSA
109,00 Ų
Regla de cinco de Lipinski
Cumple
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5ccccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC
InChI
InChI=1S/C32H38N2O8/c1-37-24-12-17(13-25(38-2)29(24)39-3)31(35)42-26-14-18-16-34-11-10-20-19-8-6-7-9-22(19)33-28(20)23(34)15-21(18)27(30(26)40-4)32(36)41-5/h6-9,12-13,18,21,23,26-27,30,33H,10-11,14-16H2,1-5H3/t18-,21+,23-,26-,27+,30+/m1/s1
Molecular Formula
C32H38N2O8
HBD / HBA
1 / 9
Enlaces Rotables
9
Átomos Pesados
42
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A rauwolfia alkaloid that depletes catecholamine and serotonin stores in nerve terminals, used historically to treat high blood pressure and certain psychiatric conditions. Like reserpine, it can cause severe depression as a side effect. Its use has been largely abandoned in favor of safer and more effective antihypertensives.
Yes, Deserpidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200515. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 8550. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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