Elexacaftor

CHEMBL4298128 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

597.7 g/mol

LogP

4.9

Phase

4

This medication works by correcting the misfolded CFTR protein that causes cystic fibrosis, helping it function more normally in the lungs. It is used in combination with other CFTR modulators for greater benefit.

Peso molecular

597,7000 g/mol

LogP

4,90

TPSA

133,00 Å²

Regla de cinco de Lipinski

No cumple

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

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SMILES

Cc1nn(C)cc1S(=O)(=O)NC(=O)c1ccc(-n2ccc(OCC(C)(C)C(F)(F)F)n2)nc1N1C[C@@H](C)CC1(C)C

InChI

InChI=1S/C26H34F3N7O4S/c1-16-12-25(5,6)35(13-16)22-18(23(37)33-41(38,39)19-14-34(7)31-17(19)2)8-9-20(30-22)36-11-10-21(32-36)40-15-24(3,4)26(27,28)29/h8-11,14,16H,12-13,15H2,1-7H3,(H,33,37)/t16-/m0/s1

Molecular Formula

C26H34F3N7O4S

HBD / HBA

1 / 11

Enlaces Rotables

8

Átomos Pesados

41

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

This medication works by correcting the misfolded CFTR protein that causes cystic fibrosis, helping it function more normally in the lungs. It is used in combination with other CFTR modulators for greater benefit.

Yes, Elexacaftor is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4298128. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 134587348. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Estructura

Datos Rápidos

Fórmula: C26H34F3N7O4S
Sinónimos: 1

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.