Erlotinib Hydrochloride
The hydrochloride salt form of erlotinib, this targeted cancer drug blocks the EGFR signaling pathway to slow the growth of EGFR-mutated tumors. The hydrochloride salt formulation is used in standard oral capsules.
Peso molecular
429,9000 g/mol
TPSA
74,70 Ų
Áreas terapéuticas
Mecanismo de acción
Reversible inhibitor of EGFR (HER1) tyrosine kinase, blocking autophosphorylation.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Reversible inhibitor of EGFR (HER1) tyrosine kinase, blocking autophosphorylation.
Estructura 2D
Cite this structure
Embed this structure
SMILES
C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1.Cl
InChI
InChI=1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H
Molecular Formula
C22H24ClN3O4
HBD / HBA
2 / 7
Enlaces Rotables
11
Átomos Pesados
30
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
The hydrochloride salt form of erlotinib, this targeted cancer drug blocks the EGFR signaling pathway to slow the growth of EGFR-mutated tumors. The hydrochloride salt formulation is used in standard oral capsules.
Reversible inhibitor of EGFR (HER1) tyrosine kinase, blocking autophosphorylation.
Yes, Erlotinib Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1079742. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 176871. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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