Etoposide
This chemotherapy drug works by blocking an enzyme that helps uncoil DNA during cell division, causing DNA damage that leads to cancer cell death. It is used to treat a variety of cancers including lung cancer, testicular cancer, and leukemia.
Peso molecular
588,6000 g/mol
LogP
0,60
TPSA
161,00 Ų
Regla de cinco de Lipinski
No cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
COc1cc([C@@H]2c3cc4c(cc3[C@@H](O[C@@H]3O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]3O)[C@H]3COC(=O)[C@H]23)OCO4)cc(OC)c1O
InChI
InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
Molecular Formula
C29H32O13
HBD / HBA
3 / 13
Enlaces Rotables
5
Átomos Pesados
42
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
This chemotherapy drug works by blocking an enzyme that helps uncoil DNA during cell division, causing DNA damage that leads to cancer cell death. It is used to treat a variety of cancers including lung cancer, testicular cancer, and leukemia.
Yes, Etoposide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL44657. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 36462. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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