Flucytosine
This antifungal medication enters fungal cells and disrupts RNA and DNA synthesis, preventing the fungus from growing and reproducing. It is often used in combination with other antifungals, particularly amphotericin B, to treat serious fungal infections such as cryptococcal meningitis.
Peso molecular
129,0900 g/mol
LogP
-0,90
TPSA
67,50 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
Nc1nc(=O)[nH]cc1F
InChI
InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)
Molecular Formula
C4H4FN3O
HBD / HBA
2 / 3
Enlaces Rotables
0
Átomos Pesados
9
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
This antifungal medication enters fungal cells and disrupts RNA and DNA synthesis, preventing the fungus from growing and reproducing. It is often used in combination with other antifungals, particularly amphotericin B, to treat serious fungal infections such as cryptococcal meningitis.
Yes, Flucytosine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1463. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3366. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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