Foslevodopa
A prodrug form of levodopa delivered under the skin to provide steady levels of the medication for Parkinson's disease. It helps reduce motor fluctuations in patients who experience unpredictable 'on' and 'off' periods.
Peso molecular
277,1700 g/mol
LogP
-4,00
TPSA
150,00 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Mecanismo de acción
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Estructura 2D
Cite this structure
Embed this structure
SMILES
N[C@@H](Cc1ccc(OP(=O)(O)O)c(O)c1)C(=O)O
InChI
InChI=1S/C9H12NO7P/c10-6(9(12)13)3-5-1-2-8(7(11)4-5)17-18(14,15)16/h1-2,4,6,11H,3,10H2,(H,12,13)(H2,14,15,16)/t6-/m0/s1
Molecular Formula
C9H12NO7P
HBD / HBA
5 / 8
Enlaces Rotables
5
Átomos Pesados
18
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A prodrug form of levodopa delivered under the skin to provide steady levels of the medication for Parkinson's disease. It helps reduce motor fluctuations in patients who experience unpredictable 'on' and 'off' periods.
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Yes, Foslevodopa is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594379. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 127766. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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