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Ganaxolone

CHEMBL1568698 Phase 4 Aprobado Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
332.5 g/mol
LogP
5.0
Phase
4

This medication is a synthetic analog of allopregnanolone, a natural neurosteroid that enhances the activity of GABA-A receptors to reduce abnormal electrical activity in the brain. It is used to treat CDKL5 deficiency disorder, a rare and severe form of childhood epilepsy that causes frequent seizures. It can be given orally as a suspension.

Peso molecular

332,5000 g/mol

LogP

5,00

TPSA

37,30 Ų

Regla de cinco de Lipinski

Cumple

Áreas terapéuticas

Epilepsia Trastorno depresivo mayor

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C

                

                

                
                

                    
InChI

                    
InChI=1S/C22H36O2/c1-14(23)17-7-8-18-16-6-5-15-13-20(2,24)11-12-21(15,3)19(16)9-10-22(17,18)4/h15-19,24H,5-13H2,1-4H3/t15-,16-,17+,18-,19-,20+,21-,22+/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C22H36O2

                    

                    
                    

                        
HBD / HBA

                        
1 / 2

                    

                    
                    

                        
Enlaces Rotables

                        
1

                    

                    
                    
                    

                        
Átomos Pesados

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Preguntas frecuentes

                

                    
                    

                        
                        

                            
This medication is a synthetic analog of allopregnanolone, a natural neurosteroid that enhances the activity of GABA-A receptors to reduce abnormal electrical activity in the brain. It is used to treat CDKL5 deficiency disorder, a rare and severe form of childhood epilepsy that causes frequent seizures. It can be given orally as a suspension.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Ganaxolone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1568698.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 6918305.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Aviso médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.