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Glycerol Phenylbutyrate

CHEMBL2105745 Phase 4 Aprobado Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
530.6 g/mol
LogP
6.7
Phase
4

Used to reduce ammonia levels in the blood for patients with certain urea cycle disorders. It works by providing an alternative pathway for the body to eliminate nitrogen waste.

Peso molecular

530,6000 g/mol

LogP

6,70

TPSA

78,90 Ų

Regla de cinco de Lipinski

No cumple

Áreas terapéuticas

Parkinson's Disease Epilepsy

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
O=C(CCCc1ccccc1)OCC(COC(=O)CCCc1ccccc1)OC(=O)CCCc1ccccc1

                

                

                
                

                    
InChI

                    
InChI=1S/C33H38O6/c34-31(22-10-19-27-13-4-1-5-14-27)37-25-30(39-33(36)24-12-21-29-17-8-3-9-18-29)26-38-32(35)23-11-20-28-15-6-2-7-16-28/h1-9,13-18,30H,10-12,19-26H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C33H38O6

                    

                    
                    

                        
HBD / HBA

                        
- / 6

                    

                    
                    

                        
Enlaces Rotables

                        
20

                    

                    
                    
                    

                        
Átomos Pesados

                        
39

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Preguntas frecuentes

                

                    
                    

                        
                        

                            
Used to reduce ammonia levels in the blood for patients with certain urea cycle disorders. It works by providing an alternative pathway for the body to eliminate nitrogen waste.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Glycerol Phenylbutyrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2105745.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 10482134.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Aviso médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.