Ibutilide
This antiarrhythmic drug is used to rapidly convert atrial fibrillation or atrial flutter to normal sinus rhythm. It works primarily by prolonging cardiac action potentials through effects on potassium and sodium ion channels. It is given by intravenous infusion in a monitored setting due to the risk of potentially life-threatening ventricular arrhythmias.
Peso molecular
384,6000 g/mol
LogP
4,00
TPSA
78,00 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1
InChI
InChI=1S/C20H36N2O3S/c1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25/h12-15,20-21,23H,4-11,16-17H2,1-3H3
Molecular Formula
C20H36N2O3S
HBD / HBA
2 / 5
Enlaces Rotables
14
Átomos Pesados
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
This antiarrhythmic drug is used to rapidly convert atrial fibrillation or atrial flutter to normal sinus rhythm. It works primarily by prolonging cardiac action potentials through effects on potassium and sodium ion channels. It is given by intravenous infusion in a monitored setting due to the risk of potentially life-threatening ventricular arrhythmias.
Yes, Ibutilide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL533. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 60753. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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